Cardiose®

Fuel performance with the power of citrus.

Metabolic efficiency for stronger performance, clinically proven.

In today’s evolving functional health and sports nutrition market, performance is no longer defined only by energy or muscle mass. It is about efficiency. Brands are looking for clinically validated ingredients that boost physical performance, improve metabolism, and deliver measurable results.

Cardiose® is engineered for maximum bioavailability offering a nonstimulant solution to today´s active consumers from everyday athletes to the active aging sector.

Vitafoods Europe 2026 banner

What is Cardiose®?

Cardiose® is a highly bioavailable, 100% natural extract from sweet oranges (Citrus sinensis), standardized in 2S-hesperidin, the  biologically active form found in nature.

Unlike conventional hesperidin, which often contains less effective 2R isomers, Cardiose® preserves the natural 2S structure through a proprietary extraction process. This results in improved absorption and greater biological activity.

Cardiose® delivers measurable results across multiple areas of physical performance and metabolic health.

Benefits of Cardiose®

Cardiose® provides a combination of metabolic and performance benefits by acting on key physiological systems involved in blood flow and recovery. Its clinically supported profile makes it suitable for a wide range of applications in functional health and active nutrition.

Pharmaceutical Solutions

Performance & Active Nutrition

  • Increases aerobic and anaerobic performance
  • Supports power output and endurance
  • Supports faster recovery
Pharmaceutical Solutions

Metabolic & Body Composition Support

  • Promotes fat oxidation and metabolic efficiency
  • Supports lean muscle development
  • Helps maintain energy balance during exercise
Pharmaceutical Solutions

Cellular Protection

  • Helps reduce oxidative stress
  • Supports a balanced inflammatory response
  • Contributes to vascular and muscle integrity

How Cardiose® Works

Cardiose® acts on the vascular-muscular axis, a key system that influences performance and recovery.

After absorption, 2S-hesperidin metabolites stimulate endothelial nitric oxide synthase (eNOS), increasing nitric oxide production. This promotes vasodilation, allowing blood vessels to relax and improving the delivery of oxygen and nutrients to tissues.

In parallel, Cardiose® helps regulate oxidative stress and inflammation, supports mitochondrial function, and improves oxygen utilization in muscle. The result is a more efficient physiological response during exercise and recovery.

Additional Information about Cardiose®

  • Clinically validated through 12 randomized, double-blind, placebo-controlled nutritional interventions
  • Effective at a daily dose of 500 mg
  • 100% natural ingredient with a solvent-free process
  • US FDA no objection letter to our GRAS dossier (GRN 796), and not Novel in Food Supplements in the EU
  • Suitable for functional health, sports nutrition, and healthy aging applications
cta-cardiose-bottom
Cardiose

For More Information about Cardiose®, Contact Us

If you are looking to develop differentiated products with clinically supported cardiovascular and performance benefits, our team is ready to help.

Contact HTBA to explore how Cardiose® can support your next product development.

    Attach your CV*:

    pdf, doc, docx, odt, ppt, odp (2Mb)

    HEALTHTECH BIO ACTIVES S.L.U., as the data controller of your personal data, will process your information to evaluate your CV and consider your application. Your data will be retained only for as long as necessary for this purpose.



    You may exercise your rights under data protection regulations by submitting a request to protecciondedatos@htba.com. For more information on the processing of your personal data, please refer to our Privacy Policy.