DiosVein® & DiosVein Forte®

Targeted Relief Solutions for Venous Health

Clinically supported citrus flavonoids for circulation, microvascular support, and venous comfort.

Venous health is a growing global concern, especially as populations age and lifestyle factors increase the prevalence of circulatory discomfort. More than half of adults experience symptoms such as leg heaviness, swelling, or visible veins, which can progress if not properly managed. To address this need, brands are looking for effective, science-backed ingredients that support circulation, microvascular function, and overall vascular health. DiosVein® and DiosVein Forte® are advanced citrus-derived solutions developed by HTBA to support venous health across different levels of comfort need, from everyday lesser discomfort to more advanced needs of a relief support.
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What is DiosVein® & DiosVein Forte®?

DiosVein® is high-quality diosmin, derived from sweet oranges and designed to support venous function, circulation, and microvascular health. Diosmin is a well-established flavonoid used as a venoactive compound to help manage symptoms associated with chronic venous conditions.
DiosVein Forte® is a micronized purified flavonoid fraction based on diosmin, combined with complementary booster flavonoids such as hesperidin. This composition enhances absorption and provides a broader mechanism of action.

Both solutions are produced using a solvent-free process and meet high pharmaceutical-grade and food standards, ensuring consistency, safety, and performance. 

Benefits of DiosVein® & DiosVein Forte®

DiosVein® and DiosVein Forte® support venous health by targeting key mechanisms involved in circulation, microvascular function, and inflammation. Their benefits are primarily focused on symptom relief and quality of life, making them highly relevant for both preventive and therapeutic formulations.

Venous Health & Circulation

  • Supports healthy blood circulation, especially in the legs
  • Promotes venous tone and vascular integrity
  • Helps maintain capillary strength and function

Relief of Venous Discomfort

  • Helps reduce leg heaviness and fatigue
  • Supports reduction of swelling and edema
  • Helps relieve discomfort associated with varicose and spider veins

Microcirculation & Fluid Balance

  • Supports capillary permeability control
  • Promotes lymphatic drainage and fluid balance
  • Helps reduce fluid accumulation in tissues

Advanced Support with DiosVein Forte®

  • Enhanced absorption through micronization
  • Broader activity thanks to multi-flavonoid composition
  • Clinically supported improvements in symptoms and quality of life across different stages of venous disease

How DiosVein® & DiosVein Forte® Works

DiosVein® and DiosVein Forte® act on multiple pathways involved in venous function and microcirculation.

They support venous tone, helping veins maintain their structure and function, which improves blood return and reduces pooling in the lower limbs. They also act on microcirculation, strengthening capillaries and improving blood flow at the tissue level.

Another key mechanism is the regulation of capillary permeability, which helps reduce fluid leakage and supports edema control. In addition, both solutions contribute to anti-inflammatory activity, helping protect the vascular endothelium and maintain vascular homeostasis

DiosVein Forte® further enhances these effects by improving absorption and delivering a combination of flavonoids that act across vascular and lymphatic systems.

Additional Information about DiosVein® & DiosVein Forte®

  • Citrus-derived flavonoid with well-established clinical use
  • Effective at doses starting from 500 mg/day for diosmin-based solutions
  • Micronized option available for enhanced absorption and consistency
  • Supported by clinical studies, meta-analyses, and international guidelines
  • Suitable for supplements and pharmaceutical applications depending on regulatory framework
  • Available in multiple formats for formulation flexibility
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For More Information, Contact Us

Contact HTBA to explore how DiosVein® and DiosVein Forte® can support your next innovation.

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